The selection of a single molecular handedness among the two possible configurations of a given molecule, or homochirality, is observed across all living matter and is a mystery in the origin of life. Here, we show that large chemical systems, are likely to undergo a spontaneous symmetry breaking toward a homochiral state as the number of chiral species increases [1]. Through an analysis of a large chemical database, we find that there is no need of very large molecules for chiral species to dominate over achiral ones; it already happens when molecules contain about 10 heavy atoms.Refs: G. Laurent, D. Lacoste, and P. Gaspard, PNAS (2021) 118 (3) e2012741118; https://doi.org/10.1073/pnas.2012741118

# Contributed Talk Session - CT03

#### Tuesday, June 15 at 06:45am (PDT)

Tuesday, June 15 at 02:45pm (BST)

Tuesday, June 15 10:45pm (KST)

# Contributed Talk Session - CT03

##### CT03-CBBS:

CBBS Subgroup Contributed Talks

**David Lacoste***Laboratory Gulliver, ESPCI, Paris*

"Emergence of homochirality in large molecular systems"**Martijn de Jong***Leiden University*

"Cellular Potts model of convergent extension can explain shape variability of gastruloids"**Robert Planque***Vrije Universiteit Amsterdam*

"Stability of a reaction pathway adaptively controlled to maximise flux"**Bime Markdonal Ghakanyuy***University of Buea, Cameroon*

"Investigating the Impact of Multiple Feeding Attempts on Mosquito Dynamics via Mathematical Models"

##### CT03-CDEV:

CDEV Subgroup Contributed Talks

**Bahti Zakirov***Francis Crick Institute*

"Active Perception during Angiogenesis: Filopodia speed up Notch selection of Tip Cells in silico and in vivo"**Eva Deinum***Wageningen University*

"Zebrastripes for life!"**Franziska Krämer***Buchmann Institute for Molecular Life Sciences*

"Investigating Mechanical Force Dynamics of Extra-Embryonic Membranes in Tribolium castaneum (part 1)"**Zoë Lange***Frankfurt Institute for Advanced Studies*

"Investigating Mechanical Force Dynamics of Extra-Embryonic Membranes in Tribolium castaneum (part 2)"

##### CT03-ECOP:

ECOP Subgroup Contributed Talks

**Eduardo Muñoz-Hernández***Complutense University of Madrid*

"Minimal complexity of subharmonics in two classes of periodic Volterra predator-prey models"**Thomas Woolley***Cardiff University*

"Locating bat roosts through the coupling of motion modelling and microphone data"**Christopher Kribs***University of Texas at Arlington*

"Competition between obligate & facultative scavengers & infection: vulture-jackal-anthrax dynamics in Etosha National Park"**Lukas Eigentler***University of Dundee*

"Spatial dynamics underpin competitive interactions within bacterial biofilms"

##### CT03-EVOP:

EVOP Subgroup Contributed Talks

**Glenn Young***Kennesaw State University*

" The interplay between costly reproduction and unpredictable environments shape the evolution of cooperative breeding"**Linh Huynh***Case Western Reserve University*

"Identifying Birth and Death Rates Separately to Disambiguate Mechanisms for the Same Observed Population Dynamics"**Enrico Sandro Colizzi***Leiden University, Origins Center*

"Evolution of genome architecture to divide labor through mutations"**Anudeep Surendran***University of Montreal, Canada*

"Population dynamics with spatial structure and an Allee effect"

##### CT03-IMMU:

IMMU Subgroup Contributed Talks

**Girma Mesfin Zelleke***AIMS-Cameroon*

"A Mathematical Understanding of the Dynamic Regulation of the Complement System on bacterial infection."**Solveig A. van der Vegt***Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, UK*

"Mathematical modelling of autoimmune myocarditis and the effects of immune checkpoint inhibitors"**Martin Lopez-Garcia***Department of Applied Mathematics, University of Leeds*

"A stochastic multi-scale model of Francisella tularensis infection"**Mohammad Aminul Islam***University at Buffalo, The State University of New York*

"Modeling the Progression of Fibrosis with Dysregulation of ACE2 in COVID19 Patients"

##### CT03-MEPI:

MEPI Subgroup Contributed Talks

**Harry Saxton***Heriot-Watt*

"Considering the effect reinfected asymptomatic individuals have on malaria transmission"**Nico Stollenwerk***BCAM, Basque Center of Applied Mathematics, Bilbao, Spain*

"The interplay between subcritical fluctuations and import: understanding COVID-19 epidemiological dynamics"**Alun Lloyd***North Carolina State University*

"Honeymoons, Divorces, Flu and Dengue: The Underappreciated Importance of Susceptible Dynamics on Control of Endemics"**Leonardo Souto Ferreira***Universidade Estadual Paulista*

"Assessing optimal vaccination scenarios in two-dose regimen with delay differential equations"

##### CT03-MFBM:

MFBM Subgroup Contributed Talks

**Gregory Szep***King's College London*

"Parameter Inference with Bifurcation Diagrams"**Sta Léa***University of Leeds, United Kingdom*

" IL-7R mathematical modelling: algebraic expressions for amplitude and EC50"**Johannes Borgqvist***Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford*

"Symmetry methods for model-construction and analysis in the context of collective cell migration"**Remus Stana***University of Leeds*

"Diffusion in a domain with inclusion"

##### CT03-MMPB:

MMPB Subgroup Contributed Talks

**Juliana Curty Faria***CFisUC, University of Coimbra*

"Fibrinogen-Mediated Erythrocyte Adhesion"**Tânia Sousa***Department of Life Sciences University of Coimbra, Coimbra, Portugal*

"How far can hydrogen peroxide travel in microcirculation?"**Gustavo Taiji Naozuka***Laboratório Nacional de Computação Científica*

"Discovery of a dynamical system from simulated tumor growth data of a hybrid multiscale model"**Rui Travasso***CFisUC, University of Coimbra*

"Adhesion modulates cell morphology and migration within dense fibrous networks"

##### CT03-ONCO:

ONCO Subgroup Contributed Talks

**Rafael Bravo***Moffitt Cancer Center*

"Investigating the impact of tissue density on tumor growth and evolution in a 3D whole-organ model of lung cancer"**Stefano Pasetto***H. Lee Moffitt Cancer Center & Research Institute*

"Intermittent hormone therapy models analysis and Bayesian-model-comparison for prostate cancer"**Kevin Murgas***Stony Brook University Dept. of Biomedical Informatics*

" Hierarchical Modeling of DNA Methylation Conservation in Colon Cancer"**Kathleen Wilkie***Ryerson University*

"Chemotherapy Induced Cachexia: Insights from a Mathematical Model"